The Human Proteoform Project
Ushering in a New Era of Personalized Medicine
Chemistry of Life Processes Institute is at the forefront of the Human Proteoform Project, a global initiative to map all the different forms of proteins (proteoforms) to diagnose, treat and prevent threats to human health.
CLP director Neil Kelleher cofounded the
Consortium for Top-Down Proteomics and now serves as president of the organization’s Board of Directors. The Consortium is a 501c3 non-profit corporation with international members from across academia, industry and government.
Its mission is to accelerate the comprehensive analysis of all human proteoforms produces from the genome providing the bridge from genotype to phenotype.
In October 2023, CLP hosted the second
International Top-Down Proteomics Conference, a gathering of more than 200 scientists in the field who share a common mission to transform medicine through proteoform-informed science and innovation.
the human proteoform project
Why proteins matter
Click on the video to the right for a brief introduction to proteomics and the anticipated impact of the Human Proteoform Project.
Take a deeper dive.
Listen to the Human Proteome Organization (HUPO)’s podcast with CLP director Neil Kelleher to learn more about the science and scope of the Human Proteoform Project. Kelleher was the 2024 recipient of HUPO’s Donald F. Hunt Distinguished Contribution Award in recognition of his “unparalleled contributions to targeted applications in top-down proteomics, natural products discovery, and chromatin biology, and celebrates his impact on proteomics research.”
