About Us

CLP pioneers protein-informed science that leads to better target for new medicines and diagnostic tools offering hope to millions of people living with disease. 

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faculty
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($ Million) in large grant applications

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(000) human proteoforms mapped

Unlocking the Power of Proteins

Chemistry of Life Processes Institute’s groundbreaking technologies for the analysis of human proteins distinguishes Northwestern as a world leader in the fast-growing field of proteomics and protein sequencing, the next great wave in discovery science. Institute faculty and clinicians in Feinberg School of Medicine work together to apply this new knowledge of protein structure and function to create more sensitive diagnostics and identify new targets for drug development and delivery.

With a bold focus on cancer and diseases of the brain, the Institute has made several important breakthroughs for people living with ALS and Alzheimer’s disease, prostate cancer, and more through our unmatched expertise in identifying and measuring all the various forms of human proteins in our cells (proteoforms).

Our goal over the next five years is to extend these transformative capabilities to new treatments and diagnostics for not only cancer and neurodegenerative diseases, but also heart, kidney and liver disease and transplant rejection. In doing so, CLP will help launch a new era of precision medicine driven by precision proteomics.

Simultaneously, CLP provides foundational research experiences and hands-on training for the next generation of scientific leaders instilling cross-disciplinary skills and methods that prepare them for successful careers in academia, medicine, industry, and other areas.

Our History and Mission

CLP’s mission is built on a legacy of developing life-changing medicine. Today’s efforts build on a legacy of developing life-changing treatments. CLP is the home of Lyrica®, a blockbuster drug that has helped millions of patients manage fibromyalgia, seizures and nerve pain.

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our research

CLP is at the forefront of the Human Proteoform Project, a global effort to map all of the different forms of proteins (proteoforms) in all of the organs and tissues in the human body. Now we are partnering with federal funding agencies and scientists across the world to realize this ambitious initiative. 

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Speeding the Discovery of Development of New Therapeutics

“At CLP, mapping the universe of human proteins is already underway, and with donor support, we’ll be able to accelerate the ability to detect human disease earlier and develop precision medicines. We’re powering drug development with truly next generation proteomics.”

Neil L. Kelleher, PhD | Director of CLP